"Coll" Gel
"ZYD'I",
"ZYD'II"
& Zyplast
These 3 dermal fillers are also a fine, a regular and a thicker form of "dermal filler" used for all the same areas of treatment as Temporary dermal filler R. It is derived from beef and thus a "Coll" Gel allergy test must be done. We then wait 28 days before treating.
- Bovine "Coll" Gel Implants and the soon to be available, Human "Coll" Gel Implants are similar to the other temporary Injectable Fillers, in that they are bio-resorbable and produce an immediate result in filling fine or deep lines, or smoothing out creases and wrinkles. They are also used for re-contouring and reshaping lips, cheeks, noses, chins, depressions and scars
- Bovine "Coll" Gel is very easy to use and generally produces a nice smooth, soft and natural feeling "implant". It is rarely lumpy and usually has a high patient satisfaction. It often does not last as long as Temporary dermal filler R, but some patients who have had both fillers prefer ""Coll" Gel" for the "softer feel." Most clients are equally happy with either type of implant filler.
- Introduced 18 years ago, Zyderm® and Zyplast® injectable "Coll" Gel implants have set the standard in filler materials for smoothing facial lines, wrinkles and scars and in providing lip border definition. Treatments supplement the skin's natural "Coll" Gel, require minimal procedure time, and provide immediate results
- Zyderm® and Zyplast® implants are composed of highly purified bovine dermal "Coll" Gel that is dispersed in phosphate buffered physiological saline containing 0.3% lidocaine. A local anaesthetic.
- These implants have been employed successfully in many areas of the body to correct distensible acne scars; atrophy from disease or trauma; glabellar frown lines; nasolabial folds; rhinoplasty, skin graft or other surgically-induced irregularities; and other soft tissue defects.
- Zyderm® and Zyplast® implants are produced in various formulations, which are appropriate for different facial areas and conditions.
Facial Applications
- Zyderm 1 implant is used to treat fine lines, wrinkles, shallow scars and thin-skinned areas.
- Zyderm 2 implant is used to treat moderate lines, wrinkles and scars.
- Zyplast implant is used to treat pronounced lines and wrinkles, scars, and thicker-skinned areas.
Key Benefits
Patients experience immediate, visible results. Treatment with Zyderm® or Zyplast® implants is an easy and effective way to smooth lines, wrinkles, scars, and to define the lip border. An immediate, visible difference in the patient's appearance may be achieved in one treatment session.
Allergy Testing
Four weeks prior to the procedure, "Coll" Gel Test Implant is administered intradermally into the volar forearm to determine if a patient has a sensitivity to the implants. Ninety-seven percent (97%) of men and women tested can be treated with Zyderm® and Zyplast® implants.
Rigorous clinical trials to determine the safety and efficacy of Zyderm® and Zyplast® "Coll" Gel implants were conducted from 1976 to 1981. This data was submitted to the Food and Drug Administration and Zyderm® and Zyplast® implants were cleared for marketing in 1981 and 1985 respectively. No other injectable "Coll" Gel implants currently on the market have undergone such extensive study.
"Human "Coll" Gel"
This is soon to be approved for use in Australia. It has been available in the USA for some months.
Building on more than two decades of safe and effective "Coll" Gel implants, CosmoDerm™ and CosmoPlast™ are new breakthroughs in facial rejuvenation.
- Human "Coll" Gel purified from natural human dermal tissue
- No skin test required
- Immediate results in a single office visit
- Formulated with lidocaine to minimize patient discomfort
- Replenishes "Coll" Gel safely and effectively
- From the market leader in "Coll" Gel Replacement Therapy®
CosmoDerm™ and CosmoPlast™ are aesthetic applications of the same tissue-engineering technology that has been successfully used in the treatment of burns and other wounds for nearly a decade. They contain human "Coll" Gel, which has been purified from dermal tissue grown under controlled laboratory conditions.
Safe and Effective
Treatment with CosmoDerm™ and CosmoPlast™ is a safe and effective way to aid in the correction of facial wrinkles, glabellar lines, nasolabial folds, vermilion borders, distensible scars and other soft tissue deficiencies. The "Coll" Gel in CosmoDerm™ and CosmoPlast™ is isolated and purified from human dermal tissue grown under controlled laboratory conditions. The starting dermal fibroblasts are rigorously screened for known pathogens, and the resultant tissue undergoes a series of tests to ensure that it is free from contaminants. In addition, as the "Coll" Gel is isolated from the tissue, it is subjected to additional viral inactivation for added safety.
Description
CosmoDerm™ and CosmoPlast™ "Coll" Gel implants are sterile devices composed of highly purified human-based "Coll" Gel that is dispersed in phosphate-buffered physiological saline containing 0.3% lidocaine. CosmoDerm™ is a non-cross-linked formulation used in the treatment of superficial lines, whereas CosmoPlast™ is cross-linked and is primarily used in the treatment of more pronounced wrinkles.
CosmoDerm1™ - Purified human-based "Coll" Gel 35 mg/ml, dispersed in saline. Indicated to treat fine lines, wrinkles and shallow scars. For thin-skinned areas. No skin test required.
CosmoPlast™ - Purified human-based "Coll" Gel 35 mg/ml, cross-linked with glutaraldehyde dispersed in saline. Indicated to treat deep lines furrows and scars. No skin test required.
Before and after "Coll" Gel examples

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